SGrade/USMLE Step 1/Biostatistics & Epidemiology
Biostatistics & Epidemiology Practice Questions
RCT vs observational designs, sensitivity/specificity and likelihood ratios, p-values and power, RR/OR, incidence vs prevalence, prevention levels, and trial phases.
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Sample questions
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A new screening test for a rare genetic disorder is evaluated. In a population of 1000 individuals, 50 truly have the disorder. The test correctly identifies 40 of these 50 individuals as positive. It also incorrectly identifies 90 individuals without the disorder as positive. What is the sensitivity of this new screening test?
Examiner's Design Intent
To assess the student's ability to accurately calculate and interpret the sensitivity of a diagnostic test, a fundamental concept in clinical practice and medical literature interpretation.
Researchers identified 300 patients diagnosed with a rare autoimmune disease and 600 healthy individuals matched for age and sex. They then interviewed all participants about their past exposure to a specific environmental toxin. What type of epidemiologic study design is described?
Examiner's Design Intent
To assess the student's ability to differentiate between fundamental epidemiologic study designs based on the description of how participants were selected and data was collected, particularly the temporal relationship b…
In a city of 100,000 people, 500 new cases of influenza were reported in January. At the end of January, 5,000 people in the city were actively infected with influenza. What is the prevalence of influenza in this city at the end of January?
Examiner's Design Intent
To assess the candidate's ability to differentiate between incidence and prevalence and correctly apply the definition of prevalence to a given scenario.
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