SGrade/USMLE Step 1/Pulmonary System
Obstructive vs restrictive PFTs, COPD and asthma, pneumonia and TB, ILD, PE, ARDS, effusions, gas exchange, pulmonary hypertension, bronchiectasis, and sleep apnea.
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A 70-year-old female, 3 days post-total hip replacement surgery, suddenly develops acute onset dyspnea, pleuritic chest pain, and tachypnea. Her vital signs include heart rate 110/min, respiratory rate 28/min, and oxygen saturation 88% on room air. Physical exam reveals a loud P2 heart sound. Which of the following is the most likely finding on imaging for this condition?
Examiner's Design Intent
The NBME designed this question to assess a student's ability to integrate clinical risk factors, acute symptoms, and physical exam findings to diagnose a pulmonary embolism, and then to recall the most specific and char…
A 32-year-old male presents to the clinic with progressive shortness of breath and a persistent cough for the past year. He denies any smoking history but notes that his father also developed severe emphysema at a young age. Pulmonary function tests show an obstructive pattern, and a chest computed tomography scan reveals panlobular emphysema, predominantly affecting the lower lobes. His liver enzymes are mildly elevated. Which of the following enzyme deficiencies is the most likely underlying cause of this patient's condition?
Examiner's Design Intent
The NBME designed this question to test a student's ability to recognize a classic, high-yield genetic disorder with multi-system involvement (pulmonary and hepatic). It assesses the integration of clinical history, imag…
A 55-year-old male presents with sudden onset fever, chills, and a productive cough of rusty-colored sputum. Physical examination reveals inspiratory crackles over the right lower lung field. A chest X-ray shows a dense consolidation localized to the right lower lobe. Which of the following organisms is the most likely cause of this patient's pneumonia?
Examiner's Design Intent
To assess the student's ability to differentiate common causes of pneumonia based on classic, high-yield clinical and radiological features, specifically identifying the hallmark presentation of Streptococcus pneumoniae.…
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