SGrade/USMLE Step 1/Cardiovascular System
Coronary territories, pressure–volume loops, murmurs, ECG, congenital heart disease, HF, shock, endocarditis, arrhythmia drugs, and biomarkers — NBME-style integration.
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A 10-year-old boy is brought to the clinic for a routine check-up. On cardiac auscultation, a loud, holosystolic murmur is heard best at the left lower sternal border, radiating to the right sternal border. Which of the following is the most likely cause of this murmur?
Examiner's Design Intent
To test the precise knowledge of cardiac murmur characteristics, specifically differentiating between various systolic murmurs based on timing, location, and radiation, a high-yield clinical reasoning skill for Step 1.
A newborn presents with cyanosis and a single S2 on auscultation. Echocardiography reveals a single great artery arising from the right ventricle and overriding a ventricular septal defect, with right ventricular outflow tract obstruction. Which congenital heart disease is most consistent with these findings?
Examiner's Design Intent
The NBME designed this question to test a student's ability to precisely differentiate between various cyanotic congenital heart diseases based on specific echocardiographic findings and classic clinical signs (cyanosis,…
A 65-year-old man presents with substernal chest pain radiating to his left arm. An electrocardiogram (ECG) shows ST-segment elevation in leads II, III, and aVF. Which coronary artery is most likely occluded?
Examiner's Design Intent
The NBME designed this question to assess a student's foundational knowledge of ECG lead localization for myocardial infarction and the corresponding coronary artery anatomy, a critical skill for clinical diagnosis and r…
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